オカザキ　ケン   Okazaki Ken   岡崎　賢    所属   医学部 医学科（東京女子医科大学病院）    職種   教授・基幹分野長
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Similar Short-Term KOOS Between Open-Wedge High Tibial Osteotomy and Total Knee Arthroplasty in Patients Over Age 60: A Propensity Score-Matched Cohort Study.
掲載誌名	正式名：Modern rheumatology 略　 称：Mod Rheumatol ISSNコード：14397609/14397595
掲載区分	国外
巻・号・頁	epub,pp.epub
著者・共著者	Sakai Mamiko, Akasaki Yukio, Akiyama Takenori, Horikawa Tomohiro, Okazaki Ken, Hamai Satoshi, Tsushima Hidetoshi, Kawahara Shinya, Kurakazu Ichiro, Kubota Kenji, Mizu-Uchi Hideki, Nakashima Yasuharu
発行年月	2022/06
概要	OBJECTIVE:The purpose of the present study was to evaluate improvement in the Knee Injury and Osteoarthritis Outcome Score (KOOS) after open-wedge high tibial osteotomy (HTO) in comparison with total knee arthroplasty (TKA) in cohorts over age 60 matched by pre-operative age, gender, body mass index (BMI), hip-knee-ankle angle (HKAA), KOOS sub-scores, and osteoarthritis (OA) grade.METHODS:Propensity score matching was performed between 162 HTO patients and 134 TKA patients. When calculating the propensity score by multivariate logistic regression analysis, the following pre-operative confounders were included: age, gender, BMI, HKAA, KOOS sub-scores, and OA grade. Consequently, a total of 55 patients were included in each group. The Student's t-test was used to analyse differences in the post-operative KOOS sub-scores between groups.RESULTS:After propensity score matching, all matched pre-operative valuables were identical, with no significant differences between the HTO and TKA group. None of the post-operative KOOS sub-scores at 1 year after surgery showed a significant difference between the HTO and TKA groups. Both groups demonstrated significant and comparable post-operative improvement in every KOOS sub-score.CONCLUSION:In patients over age 60, there was no significant difference in short-term pain relief and improvements in activity and quality of life between HTO and TKA after propensity score matching including pre-operative age, KOOS sub-scores, and OA grade. HTO is a joint preservation procedure that is valid for knee OA even in individuals over age 60.
DOI	10.1093/mr/roac052
PMID	35652607