ヤノ　コウイチロウ   YANO Kouichirou   矢野　紘一郎    所属   医学部 医学科（東京女子医科大学病院）    職種   准教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Effects of Locomotion Training on the Physical Functions and Quality of Life in Patients with Rheumatoid Arthritis: A Pilot Clinical Trial.
掲載誌名	正式名：Progress in rehabilitation medicine 略　 称：Prog Rehabil Med ISSNコード：24321354/24321354
掲載区分	国外
巻・号・頁	7,pp.20220014
著者・共著者	Mochizuki Takeshi, Kurata Aiko, Yano Koichiro, Ikari Katsunori, Okazaki Ken
発行年月	2022
概要	Objectives:This study investigated the effects of locomotion training on physical functions and quality of life in patients with rheumatoid arthritis (RA).Methods:Thirty-five patients with RA underwent locomotion training for 6 months. Health data collected from the subjects at baseline and after 6 months were the Health Assessment Questionnaire Disability Index (HAQ-DI), pain Visual Analog Scale, 10-m walking test, Timed Up-and-Go (TUG) test, single-leg standing test, Short Form-8 score with physical and mental component summaries, and 25-question Geriatric Locomotive Function Scale. The primary endpoint was a change in HAQ-DI at 6 months.Results:In terms of the primary outcome, the HAQ-DI significantly improved from 0.48 ± 0.69 at baseline to 0.27 ± 0.36 at 6 months (P=0.011). The significant secondary outcomes were a change in TUG test for comfortable walking from 9.8 ± 2.1 s at baseline to 8.9 ± 2.0 s at 6 months (P=0.002) and increased single-leg standing times for the right and left legs from 24.7 ± 23.5 s and 22.6 ± 22.8 s at baseline to 30.9 ± 22.1 s and 32.4 ± 24.1 s at 6 months (P=0.004, P <0.001), respectively.Conclusions:The findings suggest that locomotion training for 6 months may improve the HAQ-DI in patients with RA.
DOI	10.2490/prm.20220014
PMID	35434407