セキ　モモコ   Seki Momoko   関　桃子    所属   医学部 医学科（東京女子医科大学病院）    職種   助教
論文種別	原著
言語種別	英語
査読の有無	査読なし
表題	First case of a renal cyst infection caused by Desulfovibrio: a case report and literature reviw
掲載誌名	正式名：BMC Nephrology 略　 称：BMC Nephrol ISSNコード：14712369/14712369
掲載区分	国外
巻・号・頁	23(1),pp.194
著者・共著者	Okamoto Yoshiki, Miyabe Yoei, Seki Momoko, Usio Yusuke, Sato Masayo, Kasama Eri, Akiyama Kenichi, Karasawa Kazunori, Uchida Keiko, Nitta Kosaku, Moriyama Takahito, Hoshino Junichi
発行年月	2022/05/23
概要	BACKGROUND:Genus Desulfovibrio species is a sulphate-reducing anaerobic gram-negative rod that resides in the human oral cavity and intestinal tract. It was reported as the causative pathogen of bacteraemia and abdominal infections, but not renal cyst infection, and Desulfovibrio fairfieldensis has higher pathogenicity than other Desulfovibrio species.CASE PRESENTATION:A 63-year-old man was on haemodialysis for end-stage renal failure due to autosomal dominant polycystic kidney disease. On admission, he had a persistent high-grade fever, right lumbar back pain, and elevated C-reactive protein levels. His blood and urine cultures were negative. He received ciprofloxacin and meropenem; however, there was no clinical improvement. Contrast-enhanced computed tomography and plain magnetic resonance imaging revealed a haemorrhagic cyst at the upper pole of the right kidney. The lesion was drained. Although the drainage fluid culture was negative, D. fairfieldensis was detected in a renal cyst using a polymerase chain reaction. After the renal cyst drainage, he was treated with oral metronidazole and improved without any relapse.CONCLUSIONS:To the best of our knowledge, this is the first reported case of a renal cyst infection with Desulfovibrio species. D. fairfieldensis is difficult to detect, and polymerase chain reaction tests can detect this bacterium and ensure better management for a successful recovery.
DOI	10.1186/s12882-022-02803-w