イタバシ ミチオ   Itabashi Michio
  板橋 道朗
   所属   医学部 医学科
   職種   特任教授
論文種別 その他
言語種別 英語
査読の有無 査読なし
表題 Postoperative Survival in Colitis-associated Colorectal Cancer With Ulcerative Colitis in Japan: A Multicenter Analysis.
掲載誌名 正式名:Anticancer research
略  称:Anticancer Res
ISSNコード:17917530/02507005
掲載区分国外
巻・号・頁 41(5),pp.2681-2688
著者・共著者 Sugita Akira, Ikeuchi Hiroki, Funayama Yuuji, Futami Kitaro, Iiai Tsuneo, Itabashi Michio, Suzuki Yasuo
発行年月 2021/05
概要 BACKGROUND/AIM:The aim of the study was to analyze the postoperative survival of colitis-associated colorectal cancer (CAC) with ulcerative colitis (UC), and the risk factors affecting it.PATIENTS AND METHODS:A questionnaire including postoperative survival was sent to 88 hospitals that reported CAC patients in the literature up until January, 2006 and to members of the Research Group of Intractable Inflammatory Bowel Disease.RESULTS:The 5-year postoperative overall survival (OS) of 170 CAC patients was 74.2% which was similar to sporadic colorectal cancer in Japan (72.1%). Pathologic TNM stage, histological type, type of surgical procedure (proctocolectomy, segmental resection), and preoperative cancer surveillance were statistically significant factors for OS. By Cox regression analysis, pathologic TNM stage and proctocolectomy were statistically significant prognostic factors for OS.CONCLUSION:In CAC with UC, the postoperative OS was similar to sporadic colorectal cancer. Pathologic TNM stage and proctocolectomy were confirmed as important prognostic factors.
DOI 10.21873/anticanres.15049
PMID 33952499