マツイ　ケンタロウ   Matsui Kentarou   松井　健太郎    所属   医学部 医学科（東京女子医科大学病院）    職種   非常勤講師
論文種別	原著
言語種別	英語
査読の有無	査読なし
招待の有無	招待あり
表題	Social Jetlag Changes During the COVID-19 Pandemic as a Predictor of Insomnia - A Multi-National Survey Study.
掲載誌名	正式名：Nature and science of sleep 略　 称：Nat Sci Sleep ISSNコード：11791608/11791608
掲載区分	国外
巻・号・頁	13,pp.1711-1722
著者・共著者	Brandão Luiz Eduardo Mateus, Martikainen Teemu, Merikanto Ilona, Holzinger Brigitte, Morin Charles M, Espie Colin A, Bolstad Courtney J, Leger Damien, Chung Frances, Plazzi Giuseppe, Dauvilliers Yves, Matsui Kentaro, De Gennaro Luigi, Sieminski Mariusz, Nadorff Michael R, Chan Ngan Yin, Wing Yun Kwok, Mota-Rolim Sérgio Arthuro, Inoue Yuichi, Partinen Markku, Benedict Christian, Bjorvatn Bjorn, Cedernaes Jonathan
発行年月	2021/10/06
概要	Purpose:Lifestyle and work habits have been drastically altered by restrictions due to the COVID-19 pandemic. Whether the associated changes in sleep timing modulate the risk of suffering from symptoms of insomnia, the most prevalent sleep disorder, is however incompletely understood. Here, we evaluate the association between the early pandemic-associated change in 1) the magnitude of social jetlag (SJL) - ie, the difference between sleep timing on working vs free days - and 2) symptoms of insomnia.Patients and Methods:A total of 14,968 anonymous participants (mean age: 40 years; 64% females) responded to a standardized internet-based survey distributed across 14 countries. Using logistic multivariate regression, we examined the association between the degree of social jetlag and symptoms of insomnia, controlling for important confounders like social restriction extension, country specific COVID-19 severity and psychological distress, for example.Results:In response to the pandemic, participants reported later sleep timing, especially during workdays. Most participants (46%) exhibited a reduction in their SJL, whereas 20% increased it; and 34% reported no change in SJL. Notably, we found that both increased and decreased SJL, as a result of the COVID-19 pandemic, were associated with later sleep midpoint (indicating a later chronotype) as well as more recurrent and moderate-to-severe symptoms of insomnia (about 23-54% higher odds ratio than subjects with unchanged SJL). Primarily those with reduced SJL shifted their bedtimes to a later timepoint, compared with those without changes in SJL.Conclusion:Our findings offer important insights into how self-reported changes to the stability of sleep/wake timing, as reflected by changes in SJL, can be a critical marker of the risk of experiencing insomnia-related symptoms - even when individuals manage to reduce their social jetlag. These findings emphasize the clinical importance of analyzing sleep-wake regularity.
DOI	10.2147/NSS.S327365
PMID	34675720