コジマ ミツアキ   Kojima Mitsuaki
  小島 光暁
   所属   その他 その他
   職種   嘱託医師
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 Vagus nerve stimulation modulates arachidonic acid production in the mesenteric lymph following intestinal ischemia-reperfusion injury.
掲載誌名 正式名:The journal of trauma and acute care surgery
略  称:J Trauma Acute Care Surg
ISSNコード:21630763/21630755
掲載区分国外
巻・号・頁 91(4),pp.700-707
著者・共著者 Nakatsutsumi Keita, Morishita Koji, Yagi Masayuki, Doki Sanae, Watanabe Arisa, Ikegami Nahoko, Kobayashi Testuyuki, Kojima Mitsuaki, Senda Atsushi, Yamamoto Kouhei, Aiboshi Junichi, Coimbra Raul, Otomo Yasuhiro
発行年月 2021/10
概要 BACKGROUND:Inflammatory lipid mediators in mesenteric lymph (ML), including arachidonic acid (AA), are considered to play an important role in the pathogenesis of multiple-organ dysfunction after hemorrhagic shock. A previous study suggested that vagus nerve stimulation (VNS) could relieve shock-induced gut injury and abrogate ML toxicity, resulting in the prevention of multiple-organ dysfunction. However, the detailed mechanism of VNS in lymph toxicity remains unclear. The study aimed to investigate the relationship between VNS and inflammatory lipid mediators in
DOI 10.1097/TA.0000000000003345
PMID 34238858