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イシハラ ヒロキ
Ishihara Hiroki
石原 弘喜 所属 医学部 医学科（東京女子医科大学病院） 職種 助教 |
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| 論文種別 | 原著 |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | The controlling nutritional status CONUT score in patients with advanced bladder cancer after radical cystectomy. |
| 掲載誌名 | 正式名：In vivo (Athens, Greece) 略 称：In Vivo ISSNコード：0258851X/17917549 |
| 掲載区分 | 国外 |
| 巻・号・頁 | 35(2),pp.999-1006 |
| 著者・共著者 | NEMOTO Yuki†, KONDO Tsunenori*, ISHIHARA Hiroki, TAKAGI Toshio, FUKUDA Hironori, YOSHIDA Kazuhiko, IIZUKA Junpei, ISHIDA Hideki, TANABE Kazunari |
| 発行年月 | 2021/03 |
| 概要 | BACKGROUND/AIM:The impact of the controlling nutritional status (CONUT) score on oncological outcomes after radical cystectomy (RC) for advanced bladder cancer (BC) is unknown.PATIENTS AND METHODS:We retrospectively evaluated 115 patients who underwent RC for advanced BC at our department between November 2003 and February 2019. The CONUT score was calculated from serum albumin levels, total lymphocyte counts, and total cholesterol levels. Relapse-free survival (RFS), cancer-specific survival (CSS), and overall survival (OS) after RC were analyzed.RESULTS:For the CONUT score, the area under curve was 0.651 and the optimal cut-off value determined using the Youden index was 3. The high CONUT group had significantly shorter RFS, CSS, and OS than the low CONUT group. Multivariate analyses showed that the CONUT score was an independent prognostic factor of RFS, CSS, and OS.CONCLUSION:The CONUT score could be an effective predictor for survival and tolerability following RC for advanced BC. |
| DOI | 10.21873/invivo.12343 |
| PMID | 33622895 |