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ワカバヤシ ヒデタカ
Wakabayashi Hidetaka
若林 秀隆 所属 医学部 医学科（東京女子医科大学病院） 職種 教授・基幹分野長 |
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| 論文種別 | 原著 |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | Outcome of appendicular or scapular osteosarcoma treated by limb amputation in cats: 67 cases (1997-2018). |
| 掲載誌名 | 正式名：Journal of the American Veterinary Medical Association 略 称：J Am Vet Med Assoc ISSNコード：1943569X/00031488 |
| 掲載区分 | 国外 |
| 巻・号・頁 | 260(S1),pp.S24-S28 |
| 著者・共著者 | Nakano Yuko, Kagawa Yumiko, Shimoyama Yumiko, Yamagami Tetsushi, Nomura Kohji, Wakabayashi Hidetaka, Sugiyama Yoshifumi, Kobayashi Tetsuya |
| 発行年月 | 2021/12 |
| 概要 | OBJECTIVE:To evaluate the metastasis rate, survival time, and prognostic factors associated with appendicular or scapular osteosarcoma treated by limb amputation in cats.ANIMALS:67 cats with histologically confirmed appendicular or scapular osteosarcoma treated by limb amputation.PROCEDURES:This retrospective cohort study included cats with histologically confirmed appendicular or scapular osteosarcoma between January 1997 and December 2018. A questionnaire survey was conducted at veterinary clinics where limb amputation was performed. Distant metastasis, local recurrence, and lymph node metastasis rates and survival time were determined. Factors associated with distant metastasis and survival were investigated.RESULTS:The distant metastasis rate after limb amputation was 41.9% (26/62). The overall distant metastasis rate was 46.3% (31/67), including 5 cats with distant metastasis at the time of amputation. Osteosarcoma of the humerus resulted in distant metastasis in 6 of 7 cases. Osteosarcoma of the humerus was significantly associated with distant metastasis in univariate and multivariate analyses (adjusted OR, 9.56). The rate of lymph node metastasis after limb amputation was 3.0% (2/66), and the local recurrence rate was 9.0% (6/67). The median survival time was 527 days. Age and tumor location were not significantly associated with survival time.CLINICAL RELEVANCE:Distant metastasis occurs in approximately 40% of cats with appendicular or scapular osteosarcoma after limb amputation. In addition, osteosarcoma of the humerus has a particularly high incidence of distant metastasis. Detailed follow-up is therefore necessary, even after limb amputation, especially in cases of osteosarcoma of the humerus. |
| DOI | 10.2460/javma.21.04.0213 |
| PMID | 34914624 |