アリイズミ　シユンイチ   Ariizumi Shiyun'ichi   有泉　俊一    所属   医学部 医学科（東京女子医科大学病院）    職種   准教授
論文種別	症例報告
言語種別	英語
査読の有無	査読あり
表題	Abscopal complete regression of hepatocellular carcinoma with multiple pleural metastases.
掲載誌名	正式名：International cancer conference journal 略　 称：Int Cancer Conf J ISSNコード：21923183/21923183
掲載区分	国外
巻・号・頁	10(1),pp.54-58
著者・共著者	OHMATSU Kenta, HASHIMOTO Yaichiro*, KAWANISHI Miki, ISHII Yuka, KONO Sawa, KURIBAYASHI Shigehiko, ARIIZUMI Shunichi, KARASAWA Kumiko
発行年月	2021/01
概要	Hepatocellular carcinoma (HCC) with extrahepatic metastasis is rare, and its prognosis is extremely poor. There is no standard treatment for HCC with extrahepatic metastasis. We report a case of abscopal effect in HCC with multiple pleural metastases in a patient who was treated with focal radiotherapy to extrahepatic metastasis, and achieved long-term survival. We performed radiotherapy only to the tumor in inferior vena cava and the proximal pleural tumor. The regimen comprised a total dose of 30 Gy administered in ten fractions to these tumors, followed by 12 Gy administered in four fractions (a total of 42 Gy in 14 fractions) as boost irradiation to the remaining tumor, and a complete regression was achieved. There have been some case reports on abscopal effects in HCC, but no reports on patients with multiple pleural metastases. To our knowledge, this is the first case report on the abscopal effect of focal radiotherapy resulting in complete regression of distant multiple pleural metastases.
DOI	10.1007/s13691-020-00446-y
PMID	33489702