ヨシダ　タクオ   YOSHIDA Takuo   吉田　拓生    所属   医学部 医学科（東京女子医科大学病院）    職種   非常勤講師
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	The impact of sustained new-onset atrial fibrillation on mortality and stroke incidence in critically ill patients: A retrospective cohort study.
掲載誌名	正式名：Journal of critical care 略　 称：J Crit Care ISSNコード：15578615/08839441
掲載区分	国外
巻・号・頁	44,pp.267-272
著者・共著者	Yoshida Takuo, Uchino Shigehiko, Yokota Taisuke, Fujii Tomoko, Uezono Shoichi, Takinami Masanori
担当区分	筆頭著者
発行年月	2018/04
概要	PURPOSE:The purpose of the study is to evaluate the impact of sustained new-onset AF on mortality and the incidence of stroke in critically ill non-cardiac surgery patients.MATERIAL AND METHODS:This was a retrospective cohort study of non-cardiac surgery patients with new-onset AF conducted in a general intensive care unit. We compared patients remaining in AF with those restored to sinus rhythm (SR) at 6h after the onset of AF and conducted multivariable logistic regression analysis for in-hospital mortality. We also examined the impact of the cumulative time of AF duration in the first 48h on hospital outcomes.RESULTS:New-onset AF occurred in 151 of 1718 patients (9%). Patients with sustained AF after 6h (34% of 151 patients included) experienced greater in-hospital mortality than patients with SR at 6h (37% vs. 20%, p=0.033). Multivariable logistic regression analysis confirmed the association between AF at 6h and in-hospital mortality (adjusted odds ratio, 3.14; 95% confidence intervals, 1.28-7.69; p=0.012). Patients with longer AF duration had greater in-hospital mortality (p=0.043) and in-hospital ischemic stroke incidence (p=0.041).CONCLUSION:Sustained new-onset AF is associated with poor outcomes.
DOI	10.1016/j.jcrc.2017.11.040
PMID	29220756