ノナカ　マナブ   Nonaka Manabu   野中　学    所属   医学部 医学科（東京女子医科大学病院）    職種   教授・基幹分野長
論文種別	症例報告
言語種別	英語
査読の有無	査読あり
表題	Diagnostic Utility of Polymerase Chain Reaction for Paraffin-embedded Sinus Specimens for Rhinocerebral Mucormycosis Complicated by Internal Carotid Artery Thrombosis and Cerebral Infarction.
掲載誌名	正式名：Internal medicine (Tokyo, Japan) 略　 称：Intern Med ISSNコード：13497235/09182918
掲載区分	国内
巻・号・頁	pp.1-4
総ページ数	4
著者・共著者	Maeda Yukiko, Toda Kunio, Toi Sono, Yano Tetsundo, Iijima Mutsumi, Shimizu Yuko, Nagashima Yoji, Itakura Yasutomo, Iguchi Shigekazu, Kikuchi Ken, Shibuya Kazutoshi, Nonaka Manabu, Kitagawa Kazuo
発行年月	2021/03
概要	We herein report a 73-year-old man who experienced cerebral infarction caused by infection with a Mucromycocetes species. A delay in anti-fungal treatment might result in a lethal clinical outcome. We were unable to establish an accurate diagnosis based on histological findings and cerebrospinal fluid culture. Therefore, we performed polymerase chain reaction (PCR) using paraffin-embedded specimens, and based on the findings, successfully started administering anti-fungal treatment. We suggest that PCR using sinus specimens be applied when mucormycosis is suspected as an etiology of cerebral infarction and a confirmative diagnosis cannot be established based on the results of pathological examinations or cerebrospinal fluid culture.
DOI	10.2169/internalmedicine.6809-20
PMID	33678746