キクチ　ケン   Kikuchi Ken   菊池　賢    所属   医学部 医学科（東京女子医科大学病院）    職種   教授
論文種別	症例報告
言語種別	英語
査読の有無	査読あり
表題	Erosive polyarthritis caused by sepsis due to a novel species of Streptobacillus notomytis.
掲載誌名	正式名：Modern rheumatology case reports 略　 称：Mod Rheumatol Case Rep ISSNコード：24725625/24725625
掲載区分	国外
巻・号・頁	4(1),pp.95-98
著者・共著者	Kusuda Takeshi†*, Ryoko Asami, Yoshishige Masuda, Tanaka Masashi, Yoshida Atsushi, Kikuchi Ken, Sugihara Takahiko
発行年月	2020/01
概要	Rat-bite fever (RBF) is characterized by fever, rash and arthritis, mainly caused by Streptobacillus moniliformis. We present a case of inflammatory erosive polyarthritis with sepsis caused by Streptobacillus notomytis, a novel species isolated from S. moniliformis. A 67-year-old man presented with fever, purpura and peripheral arthritis. After blood cultures were performed, loxoprofen administration was initiated. Arthritis partially improved, but left first metatarsophalangeal (MTP) arthritis persisted. A gram-negative rod was detected in the blood culture, and meropenem administration was started that improved arthritis. Ultrasonography and computed tomography revealed bone erosion in the left first MTP joint, leading to the diagnosis of septic arthritis. 16S rRNA gene sequence analysis revealed that this strain was S. notomytis. Further questioning revealed the patient may have had contact with rats. It is essential to consider Streptobacillus infection in the differential diagnosis of erosive polyarthritis.
DOI	10.1080/24725625.2019.1655246
PMID	33086954