オオツキ　ミチオ   OOTSUKI Michio   大月　道夫    所属   医学部 医学科（東京女子医科大学病院）    職種   教授・基幹分野長
論文種別	症例報告
言語種別	英語
査読の有無	査読あり
表題	Asymptomatic Pontine Lesion and Diabetic Amyotrophy after Rapid Improvement of Poor Glycemic Control in a Patient with Type 1 Diabetes
掲載誌名	正式名：Internal Medicine 略　 称：Intern Med ISSNコード：09182918
掲載区分	国内
巻・号・頁	58(23),pp.3433-3439
著者・共著者	Shimizu, Y. Kozawa, J. Hayakawa, T. Sakai, Y. Kimura, T. Kitamura, T. Murase, S. Tanaka, H. Maeda, N. Otsuki, M. Matsuoka, T. Mochizuki, H. Iwahashi, H. Shimomura, I.
発行年月	2019
概要	We herein report a 28-year-old woman with type 1 diabetes with an asymptomatic pontine lesion and diabetic amyotrophy. She had suffered from diabetes from 10 years old. Treatment in a hospital reduced the hemoglobin A1c level from 14.2% to 7.2% for approximately 2 months. She suffered from acute-onset pain and weakness of the lower limb muscles without central nervous system manifestations. Magnetic resonance imaging showed high-intensity lesions at the brainstem and lower limb muscles on T2-weighted images. These findings and symptoms gradually resolved. Rapid treatment of poor glycemic control might increase the risk of asymptomatic pontine lesions and diabetic amyotrophy.
DOI	10.2169/internalmedicine.2835-19
文献番号	31391398