シヨウダ　モリオ   Shiyouda Morio   庄田　守男    所属   医学部 医学科（東京女子医科大学病院）    職種   寄附部門教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Efficacy of catheter ablation for patients with atrial fibrillation and atrial septal defect.
掲載誌名	正式名：Journal of cardiovascular electrophysiology 略　 称：J Cardiovasc Electrophysiol ISSNコード：15408167/10453873
掲載区分	国外
巻・号・頁	32(2),pp.279-286
著者・共著者	Ogiso Masataka, Ejima Koichiro, Shoda Morio, Sugiyama Hisashi, Kato Ken, Tanaka Hiroyuki, Ohki Hirotaka, Miura Masaru, Hagiwara Nobuhisa
発行年月	2021/02
概要	INTRODUCTION:Given that few studies investigated the efficacy of catheter ablation (CA) in patients with paroxysmal atrial fibrillation (AF) and atrial septal defect (ASD), this study evaluated its effectiveness in patients with paroxysmal AF and ASD.METHODS AND RESULTS:Of the 216 patients who underwent ASD device closure at two hospitals, 36 patients had paroxysmal AF. After April 2012, CA for AF was performed before ASD device closure (ASD-CA group; n = 20). The ASD-CA group had a significantly higher AF-free survival rate after ASD device closure compared to patients without CA for AF before ASD device closure (ASD-non-CA group; n = 16) (ASD-CA group: 2 patients vs. ASD-non-CA group: 9 patients; follow-up period: 4.2 ± 2.5 years; log-rank p = .01). In addition, the AF-free survival rates were similar between the ASD-CA group and 80 paroxysmal AF patients who underwent CA without any detectable structural heart disease (non-SHD-CA group). The two groups were matched by propensity scores for age, sex, and left atrium dimension (ASD-CA group: 2 patients vs. non-SHD-CA group: 5 patients; follow-up period: 3.3 ± 1.8 years; log-rank p = .28).CONCLUSION:CA for AF before ASD device closure might be an effective treatment option for patients with paroxysmal AF and ASD.
DOI	10.1111/jce.14862
PMID	33382508