ハセガワ　タイジ   HASEGAWA Taiji   長谷川　泰司    所属   医学部 医学科（東京女子医科大学病院）    職種   講師
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Misalignment between center of foveal avascular zone and center of foveal photoreceptors in eyes with idiopathic epiretinal membrane.
掲載誌名	正式名：Retina (Philadelphia, Pa.) 略　 称：Retina ISSNコード：15392864/0275004X
掲載区分	国外
巻・号・頁	41(8),pp.1635-1643
著者・共著者	Hasegawa Taiji, Kawaguchi Ai, Arakawa Hisaya, Maruko Ichiro, Iida Tomohiro
担当区分	筆頭著者,責任著者
発行年月	2021/08
概要	PURPOSE:To determine the degree of misalignment between the center of foveal avascular zone (FAZ) and the center of foveal photoreceptors in eyes with an idiopathic epiretinal membrane (ERM).METHODS:We reviewed the medical records of 61 eyes with an idiopathic ERM. A 3×3 mm area centered on the fovea was scanned with optical coherence tomography angiography (OCTA) before and at 6 months after surgery. The center of FAZ and the center of foveal photoreceptors were detected by en face OCTA images and sequential OCT B-sections in the macular region. The presence or absence of ectopic inner foveal layers (EIFLs) was also evaluated.RESULTS:The mean distance from the center of foveal photoreceptors to the center of FAZ was 111.7 ± 106.8 μm in eyes with preoperative ERM. This distance was significantly correlated with the preoperative central foveal thickness (r = 0.33, P = 0.0104). Preoperatively, the EIFLs were present in 27 (44.3%) of 61 eyes. The foveal misalignment was greater in eyes with EIFLs than in those without EIFLs (158.6 ± 140.0 μm vs 74.4 ± 45.4 μm, P < 0.0003). At 6 months after ERM surgery, the foveal misalignment was significantly reduced to 73.7 ± 48.0 μm (P = 0.0018).CONCLUSION:Determining the degree of misalignment between center of FAZ and center of foveal photoreceptors might be a useful way to evaluate the degree of ERM traction.
DOI	10.1097/IAE.0000000000003064
PMID	33315819