シミズ　ユウコ   Shimizu Yuuko   清水　優子    所属   医学部 医学科（東京女子医科大学病院）    職種   教授
論文種別	原著
言語種別
査読の有無	査読あり
表題	[The MG-QOL15 Japanese version: validation and associations with clinical factors].
掲載誌名	正式名：Rinsho shinkeigaku = Clinical neurology 略　 称：Rinsho Shinkeigaku ISSNコード：18820654/0009918X
掲載区分	国内
巻・号・頁	52(11),1043-6頁
著者・共著者	Masuda Masayuki, Utsugisawa Kimiaki, Suzuki Shigeaki, Nagane Yuriko, Ito Suguru, Kabasawa Chiaki, Suzuki Yasushi, Shimizu Yuko, Utsumi Hiroya, Fujihara Kazuo, Uchiyama Shinichiro, Suzuki Norihiro
発行年月	2012/11
概要	We produced a Japanese translation of the 15-item myasthenia gravis (MG)-specific quality of life (QOL) scale (MG-QOL15), assessed its reliability and validity, and examined clinical factors affecting the self-perceived QOL in MG. Consecutive 327 patients with MG seen at six neurological centers were evaluated. All patients completed an MG-QOL15 Japanese version (MG-QOL15-J), the Beck Depression Inventory-Second Edition (BDI-II), and a generic health-related QOL questionnaire, the SF-36. Disease severity was determined according to the MG Foundation of America (MGFA) quantitative MG score and the MG composite. The MG-QOL15-J exhibited adequate internal reliability, test-retest repeatability, and concurrent validity with SF-36, disease severity, and known-patient groups categorized by MGFA postintervention status. Multivariate analysis revealed severity, dose of oral corticosteroids, and BDI-II as independent factors negatively affecting QOL. The MG-QOL15-J is anticipated to be a valuable clinical measure of QOL in Japanese patients with MG.
DOI	10.5692/clinicalneurol.52.1043
PMID	23196510