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ムラガキ ヨシヒロ
Muragaki Yoshihiro
村垣 善浩 所属 医学部 医学科（東京女子医科大学病院） 職種 客員教授 |
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| 論文種別 | 原著 |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | Reliability of Residual Tumor Estimation Based on Navigation Log. |
| 掲載誌名 | 正式名：Neurologia medico-chirurgica 略 称：Neurol Med Chir (Tokyo) ISSNコード：13498029/04708105 |
| 掲載区分 | 国外 |
| 巻・号・頁 | 60(9),pp.458-467 |
| 著者・共著者 | YAMADA Hiroyuki†, MARUYAMA Takashi, KONISHI Yoshiyuki, MASAMUNE Ken, MURAGAKI Yoshihiro |
| 発行年月 | 2020/08/15 |
| 概要 | The mass of residual tumors has previously been estimated using time-series records of the position of surgical instruments acquired from neurosurgical navigation systems (navigation log). This method has been shown to be useful for rapid evaluation of residual tumors during resection. However, quantitative analysis of the method's reliability has not been sufficiently reported. The effect of poor log coverage is dominant in previous studies, in that it did not highlight other disturbance factors, such as intraoperative brain shift. We analyzed 25 patients with a high log-acquisition rate that was calculated by dividing the log-available time by the instrument-use time. We estimated the region of resection using the trajectory of surgical instrument that was extracted from the navigation log. We then calculated the residual tumor region and measured its volume as log-estimation residual tumor volume (RTV). We evaluated the correlation between the log-estimation RTV and the RTV in the post-resection magnetic resonance (MR) image. We also evaluated the accuracy of detecting the residual tumor mass using the estimated residual tumor region. The log-estimation RTV and the RTV in the post-resection MR image were significantly correlated (correlation coefficient = 0.960; P <0.001). The presence of patient-wise residual tumor mass was detected with a sensitivity of 81.8% and a specificity of 92.9%. The individual residual tumor mass was detected with a positive predictive value of 72%. Estimation of residual tumor with adequate log coverage appears to be a suitable method with a high reliability. This method can support rapid decision-making during resection. |
| DOI | 10.2176/nmc.oa.2020-0042 |
| 文献番号 | U918170005<Pre 医中誌> |
| PMID | 32801273 |