イチノエ　アキマサ   Ichinoe Akimasa   一戸　晶元    所属   医学部 医学科（附属足立医療センター）    職種   講師
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Retrospective Analysis of Concurrent Chemoradiation with Triweekly Cisplatin plus 5-Fluorouracil Versus Weekly Cisplatin in Cervical Cancer.
掲載誌名	正式名：Anticancer research 略　 称：Anticancer Res ISSNコード：02507005/17917530
巻・号・頁	35(6),pp.3447-3454
著者・共著者	KENZO SONODA†, HIDEAKI YAHATA, AKIMASA ICHINOE, KAORU OKUGAWA, EISUKE KANEKI, YOSHIAKI KAWANO, HIRONORI KENJO, TATSUHIRO OHGAMI, HIROSHI YAGI, SAIJI OHGA, KAORI ASAI, KATSUMASA NAKAMURA, HIROSHI HONDA, KIYOKO KATO*
発行年月	2015
概要	Background/Aim: Concurrent chemoradiation (CCRT) is the standard treatment for locally advanced cervical cancer. The purpose of the study was to compare the outcomes of triweekly cisplatin plus 5-fluorouracil and weekly cisplatin regimens. Patients and Methods: We retrospectively reviewed data from 91 patients with stage IB1-IVA cervical cancer. Results: Out of 91 patients, 48 received triweekly CCRT and 43 received weekly CCRT. For triweekly CCRT, patients received a median of two chemotherapy cycles and median total doses of cisplatin and 5-fluorouracil were 210 mg/body and 8,525 mg/body, respectively. For weekly CCRT, patients received a median of five chemotherapy cycles and the median total dose of cisplatin was 252 mg/body. No statistically significant differences in overall survival or progression-free survival were noted between the two groups. Conclusion: Both triweekly CCRT and weekly CCRT appear to have similar efficacy for cervical cancer patients, but the toxicities were better tolerable in weekly CCRT.