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ハシモト ヤスノブ
Hashimoto Yasunobu
橋本 恭伸 所属 医学部 医学科（東京女子医科大学病院） 職種 講師 |
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| 論文種別 | 原著 |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | Follow-up Survey of Donor Candidates for Living Related Kidney Transplantation With Prostate Cancer. |
| 掲載誌名 | 正式名：Transplantation proceedings 略 称：Transplant Proc ISSNコード：18732623/00411345 |
| 掲載区分 | 国外 |
| 巻・号・頁 | 50(8),pp.2338-2341 |
| 著者・共著者 | HataKeisuke†, IizukaJunpei*, HashimotoYasunobu, TakagiToshio, KondoTsunenori, OmotoKazuya, ShimizuTomokazu, OkumiMasayoshi, InuiMasashi, IshidaHideki, TanabeKazunari |
| 担当区分 | 最終著者 |
| 発行年月 | 2018/10 |
| 概要 | INTRODUCTION:With the increasing number of elderly kidney donor candidates due to the lack of available donors, prostate cancer has sometimes been detected in these candidates during pretransplant screening examinations. There are currently no guidelines or consensus on prostate cancer screening and treatment in donors. We retrospectively evaluated the clinical course of donor candidates with prostate cancer.METHODS:Between January 2006 and December 2016, 9 donor candidates for living related kidney transplantation were incidentally diagnosed with prostate cancer at our institution. All male kidney transplant donor candidates routinely received prostate-specific antigen (PSA) testing. The patients with PSA levels > 4.0 ng/mL underwent prostate biopsies. For future kidney transplantation, treatment for localized prostate cancer was prostatectomy.RESULTS:Seven low- or intermediate-risk patients according to the D'Amico risk classification underwent endoscopic prostatectomy, while 2 high-risk patients underwent high dose-rate brachytherapy to prioritize prostate cancer treatment. Of the 7 who underwent surgery, 3 patients ultimately became living related kidney transplantation donors for their wives. There was no recurrence of PSA elevation after treatment.CONCLUSION:This study showed that donor candidates with prostate cancer could safely donate a kidney after a thorough evaluation to exclude those with high-risk prostate cancer. Transmission of prostate cancer through kidney transplantation seems unlikely and robot-assisted laparoscopic prostatectomy may be feasible for donor candidates with localized prostate cancer. |
| DOI | 10.1016/j.transproceed.2018.03.036 |
| PMID | 30316354 |