ストウ　チカコ   Sutou Chikako   須藤　史子    所属   医学部 医学科（附属足立医療センター）    職種   教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Effect of perioperative glycemic control in progression of diabetic retinopathy and maculopathy.
掲載誌名	正式名：Archives of ophthalmology (Chicago, Ill. : 1960) 略　 称：Arch Ophthalmol ISSNコード：00039950/00039950
掲載区分	国外
巻・号・頁	124(1),pp.38-45
著者・共著者	Suto Chikako†, Hori Sadao, Kato Satoshi, Muraoka Kanemitsu, Kitano Shigehiko
担当区分	筆頭著者,責任著者
発行年月	2006/01
概要	OBJECTIVE:To evaluate the contribution of perioperative glycemic control to progression of diabetic retinopathy and maculopathy.METHODS:Postoperative progression of diabetic retinopathy and maculopathy were compared in 87 patients with type 2 diabetes mellitus who underwent monocular phacoemulsification cataract surgery performed by a single surgeon. Twenty-seven patients had had poor glycemic control preoperatively and underwent rapid preoperative glycemic correction; 30 patients had poor control preoperatively that was not corrected postoperatively; and 30 patients had good preoperative glycemic control. The grade of diabetic retinopathy and maculopathy in the operated-on eye and the fellow eye was assessed preoperatively and for 12 months postoperatively.RESULTS:There were no significant differences in the progression rate of diabetic retinopathy among the 3 groups (P = .27). However, the progression rate of diabetic maculopathy was significantly higher in the group that underwent rapid control than in the other 2 groups (P = .02). Patients with moderate to severe nonproliferative diabetic retinopathy preoperatively in the rapid control group had significantly higher progression rates of diabetic retinopathy and maculopathy (P = .002 and .008, respectively).CONCLUSIONS:Rapid preoperative glycemic control should be avoided in patients with moderate to severe nonproliferative diabetic retinopathy because it may increase the risk of postoperative progression of retinopathy and maculopathy.
DOI	10.1001/archopht.124.1.38
PMID	16401783