ナギ　サチヨ   Nagi Sachiyo   凪　幸世    所属   医学部 医学科    職種   助教
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Risk factors and spatial distribution of Schistosoma mansoni infection among primary school children in Mbita District, Western Kenya.
掲載誌名	正式名：PLoS neglected tropical diseases 略　 称：PLoS Negl Trop Dis ISSNコード：19352735/19352727
掲載区分	国外
巻・号・頁	24(8(7)),pp.e2991
著者・共著者	Nagi Sachiyo, Chadeka Evans A, Sunahara Toshihiko, Mutungi Faith, Justin Yombo K Dan, Kaneko Satoshi, Ichinose Yoshio, Matsumoto Sohkichi, Njenga Sammy M, Hashizume Masahiro, Shimada Masaaki, Hamano Shinjiro
担当区分	筆頭著者
発行年月	2014/07
概要	BACKGROUND:An increasing risk of Schistosoma mansoni infection has been observed around Lake Victoria, western Kenya since the 1970s. Understanding local transmission dynamics of schistosomiasis is crucial in curtailing increased risk of infection.METHODOLOGY/PRINCIPAL FINDINGS:We carried out a cross sectional study on a population of 310 children from eight primary schools. Overall, a total of 238 (76.8%) children were infected with S. mansoni, while seven (2.3%) had S. haematobium. The prevalence of hookworm, Trichuris trichiura and Ascaris lumbricoides were 6.1%, 5.2% and 2.3%, respectively. Plasmodium falciparum was the only malaria parasite detected (12.0%). High local population density within a 1 km radius around houses was identified as a major independent risk factor of S. mansoni infection. A spatial cluster of high infection risk was detected around the Mbita causeway following adjustment for population density and other potential risk factors.CONCLUSIONS/SIGNIFICANCE:Population density was shown to be a major factor fuelling schistosome infection while individual socio-economic factors appeared not to affect the infection risk. The high-risk cluster around the Mbita causeway may be explained by the construction of an artificial pathway that may cause increased numbers of S. mansoni host snails through obstruction of the waterway. This construction may have, therefore, a significant negative impact on the health of the local population, especially school-aged children who frequently come in contact with lake water.
DOI	10.1371/journal.pntd.0002991
PMID	25058653