クロダ ハジメ
Kuroda Hajime
黒田 一 所属 医学部 医学科(附属足立医療センター) 職種 教授 |
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論文種別 | 原著 |
言語種別 | 英語 |
査読の有無 | 査読あり |
表題 | Overexpression of Her2/neu, estrogen and progesterone receptors in invasive micropapillary carcinoma of the breast. |
掲載誌名 | 正式名:Breast cancer (Tokyo, Japan) 略 称:Breast Cancer ISSNコード:13406868/13406868 |
掲載区分 | 国外 |
巻・号・頁 | 11(3),pp.301-6 |
著者・共著者 | Kuroda Hajime†*, Sakamoto Goi, Ohnisi Kiyoshi, Itoyama Shinji |
担当区分 | 筆頭著者,責任著者 |
発行年月 | 2004 |
概要 | BACKGROUND:Invasive micropapillary carcinoma (IMC) of the breast is a rare subtype of breast carcinoma that has an extremely high incidence of lymph node metastasis and poor clinical outcome. Furthermore, there has been interest in the prognostic markers related to the biological characteristics of breast carcinoma, such as the status of Her2/neu, estrogen receptor (ER) and progesterone receptor (PgR).MATERIALS AND METHODS:We reviewed 671 cases of primary breast carcinoma which were surgically resected between 1990 and 2003. Of these, 27 cases of invasive ductal carcinoma of the breast with a pure or partial micropapillary component were reported. Tests for Her2/neu protein, estrogen receptor (ER) and progesterone receptor (PgR) were performed on paraffin sections. The relationship among these markers was analyzed and statistical significance determined by chi-square test.CONCLUSION:The rate of Her2/neu protein overexpression, ER and PgR status was quite similar to those of common breast carcinomas. |
DOI | 10.1007/BF02984553 |
PMID | 15550850 |