ナカジマ　レイコ   Nakajima Reiko   中島　怜子    所属   医学部 医学科（東京女子医科大学病院）    職種   助教
論文種別	総説
言語種別	英語
査読の有無	査読あり
表題	Pathogenesis and FDG-PET/CT findings of Epstein-Barr virus-related lymphoid neoplasms.
掲載誌名	正式名：Annals of nuclear medicine 略　 称：Ann Nucl Med ISSNコード：18646433/09147187
掲載区分	国内
巻・号・頁	31(6),pp.425-436
著者・共著者	Toriihara Akira, Nakajima Reiko, Arai Ayako, Nakadate Masashi, Abe Koichiro, Kubota Kazunori, Tateishi Ukihide
担当区分	2nd著者
発行年月	2017/07
概要	Epstein-Barr virus (EBV) is one of the most common viruses, infecting more than 90% of the adult population worldwide. EBV genome is detected in some lymphoid neoplasms. Not only their histopathological subtypes, but also their backgrounds and their clinical courses are variable. A number of B-cell lymphoproliferative disorders associated with the immunocompromised state are related to EBV infection. The incidences of these disorders have been increasing along with generalization of organ transplantations and use of immunosuppressive treatments. Furthermore, some EBV-positive lymphoma can also occur in immunocompetent patients. While evaluating patients with generalized lymphadenopathy of unknown cause by positron emission tomography/computed tomography with 2-deoxy-2-[18F]fluoro-D-glucose (FDG-PET/CT), the possibility of lymphoid neoplasms should be considered in some patients, and a careful review of the background and previous history of the patients is necessary. In this review article, we describe the pathogenesis of EBV-related lymphoid neoplasms and then present FDG-PET/CT images of representative diseases. In addition, we also present a review of other EBV-related diseases, such as infectious mononucleosis and nasopharyngeal carcinoma.
DOI	10.1007/s12149-017-1180-5
PMID	28497429