ナカミゾ　ムネナガ   Nakamizo Munenaga   中溝　宗永    所属   医学部 医学科（東京女子医科大学病院）    職種   特任教授
論文種別	症例報告
言語種別	英語
査読の有無	査読あり
表題	Three cases of carcinoma of the hypopharynx developing as metachronous second primary cancers after total laryngectomy with radiotherapy for carcinoma of the larynx.
掲載誌名	正式名：Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 略　 称：J Nippon Med Sch ISSNコード：13473409/13454676
掲載区分	国外
巻・号・頁	78(4),pp.26１-266
著者・共著者	YOKOSHIMA Kazuhiko, NAKAMIZO Munenaga, KOKAWA Takayuki, INAI Shunta, SAKANUSHI Atsuko, SAITO Yukiko, OHKUBO Kimihiro
担当区分	2nd著者
発行年月	2011
概要	We describe 3 cases of metachronous hypopharyngeal cancer developing after laryngeal cancer had been treated with both radiotherapy and total laryngectomy. All 3 patients were men, 2 were 89 years old, and 1 was 65 years old. All patients had undergone total laryngectomy and radiotherapy for cancer for the glottis more than 20 years earlier. All patients underwent total hypopharyngectomy with jejunal free flap reconstruction. Surgery was complicated by scars from previous cancer treatment, and highly sophisticated surgical skills are needed, especially for preparing the recipient vessels. The postoperative period was largely uneventful and without fatal complications, however, 2 of the 3 patients died of distant metastasis 22 months and 31 months after surgery.
DOI	10.1272/jnms.78.261
PMID	21869562