ワカバヤシ　ヒデタカ   Wakabayashi Hidetaka   若林　秀隆    所属   医学部 医学科（東京女子医科大学病院）    職種   教授・基幹分野長
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Predictive Validity of Body Mass Index Cut-off Values Used in the GLIM Criteria for discriminating Severe and Moderate Malnutrition Based on In-Patients With Pneumonia in Asian Populations.
掲載誌名	正式名：JPEN. Journal of parenteral and enteral nutrition 略　 称：JPEN J Parenter Enteral Nutr ISSNコード：19412444/01486071
掲載区分	国外
巻・号・頁	36,pp.1-11
著者・共著者	Shimizu Akio, Maeda Keisuke, Wakabayashi Hidetaka, Nishioka Shinta, Nagano Ayano, Kayashita Jun, Fujishima Ichiro, Momosaki Ryo
発行年月	2020/07
概要	BACKGROUND:This study aimed to investigate the predictive validity of the previously reported body mass index (BMI) cut-off values of the Global Leadership Initiative on Malnutrition (GLIM) criteria for patients with pneumonia in Asian populations using a nationwide registry database.METHODS:The study included 26,098 (2,282 patients aged <70 years and 23,784 patients aged ≥70 years) patients with pneumonia aged ≥65 years who were enrolled in the Japan Medical Data Center database between April 2014 and December 2018. Malnutrition was diagnosed using the GLIM criteria, and the severity of malnutrition was diagnosed on using a BMI cut-off value of <17.0 kg/m2 and <17.8 kg/m2 for patients aged <70 years and ≥70 years, respectively. Multivariate analysis was performed to determine whether the severity of malnutrition based on BMI was associated with poor clinical outcomes such as 30-day in-hospital mortality, length of hospital stay (LOS), and 30-day readmission.RESULTS:A total of 14.7% and 24.1% of patients aged <70 years and ≥70 years, respectively, experienced severe malnutrition. Severe malnutrition was indsependently associated with 30-day in-hospital mortality (hazard ratio [HR], 1.19; 95% confidence interval [CI], 1.05-1.34), prolonged LOS (coefficient, 5.13; 95%CI, 4.31-5.94), and 30-day readmission (HR, 2.28; 95%CI, 1.89-2.75) in patients aged ≥70 years; however, only prolonged LOS was independently associated with patients aged <70 years (coefficient, 3.27; 95%CI, -0.24-6.78).CONCLUSION:The BMI cut-off values might be valid for patients with pneumonia aged ≥70 years in Asian populations. Further investigation is required to validate the cut-off value for older adults aged <70 years. <PE-FRONTEND> This article is protected by copyright. All rights reserved.
DOI	10.1002/jpen.1959
PMID	32677042