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オノ マサフミ
Ono Masafumi
小野 正文 所属 医学部 医学科（附属足立医療センター） 職種 非常勤講師 |
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| 論文種別 | 原著 |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | Complications of radiofrequency ablation for hepatocellular carcinoma in a multicenter study: An analysis of 16 346 treated nodules in 13 283 patients. |
| 掲載誌名 | 正式名：Hepatology research : the official journal of the Japan Society of Hepatology 略 称：Hepatol Res ISSNコード：1872034X/13866346 |
| 掲載区分 | 国内 |
| 巻・号・頁 | 42(11),pp.1058-64 |
| 著者・共著者 | Koda Masahiko, Murawaki Yoshikazu, Hirooka Yasuaki, Kitamoto Mikiya, Ono Masafumi, Sakaeda Hiroshi, Joko Kouji, Sato Shuichi, Tamaki Katsuyoshi, Yamasaki Takahiro, Shibata Hiroshi, Shimoe Toshinari, Matsuda Tadakazu, Toshikuni Nobuyuki, Fujioka Shin-Ichi, Ohmoto Kenji, Nakamura Shinichiro, Kariyama Kazuya, Aikata Hiroshi, Kobayashi Yoshiyuki, Tsutsui Akemi |
| 発行年月 | 2012/11 |
| 概要 | AIM: We surveyed multiple centers to identify types and frequency of complications and mortality rate associated with radiofrequency ablation (RFA) of hepatocellular carcinoma (HCC).METHODS: We distributed a questionnaire developed by members of the Chugoku-Shikoku Society for the Local Ablation Therapy of Hepatocellular Carcinoma to 20 centers and analyzed types and frequency of complications and mortality rate.RESULTS: In total, 16 346 nodules were treated in 13 283 patients between January 1999 and November 2010. Five patients (0.038%) died: two from intraperitoneal hemorrhage, and one each from hemothorax, severe acute pancreatitis and perforation of the colon. In 16 346 treated nodules, 579 complications (3.54%) were observed, including 78 hemorrhages (0.477%), 276 hepatic injuries (1.69%), 113 extrahepatic organ injuries (0.691%) and 27 tumor progressions (0.17%). The centers that treated a large number of nodules and performed RFA modifications, such as use of artificial ascites, artificial pleural effusion and bile duct cooling, had low complication rates.CONCLUSION: This study confirmed that RFA is a low-risk treatment for HCC and that sufficient experience and technical skill can reduce complications. |
| DOI | 10.1111/j.1872-034X.2012.01025.x |
| PMID | 22583706 |