マスイ　ケンタ   Masui Kenta   増井　憲太    所属   医学部 医学科    職種   准教授
論文種別	症例報告
言語種別	英語
査読の有無	査読なし
表題	A case of lymphangioleiomyomatosis with diffuse large B-cell lymphoma: Usefulness of FDG-PET.
掲載誌名	正式名：Respiratory medicine case reports 略　 称：Respir Med Case Rep ISSNコード：22130071/22130071
掲載区分	国外
巻・号・頁	29,pp.100999
著者・共著者	ORIMO Mami†, KONDO Mitsuko, TAKEYAMA Kiyoshi, MASUI Kenta, TANAKA Junji, TAGAYA Etsuko
発行年月	2020
概要	Lymphangioleiomyomatosis (LAM) is characterized by cystic lung disease, abdominal tumor and involvement of the axial lymph nodes. We report a very rare case of LAM with malignant lymphoma. A 51-year-old female had medical history of recurrent pneumothorax and nephrectomy for a left renal angiomyolipoma and was diagnosed with LAM by video-assisted thoracoscopic surgery at the age of 30. She presented with left neck mass. Computed tomography and magnetic response imaging showed multiple enlarged cervical lymph nodes. 18F-fluorodeoxyglucose-positron emission tomography (FDG-PET) showed abnormal uptake in the mass. We suspected a malignant tumor or extrapulmonary lesion of LAM, and performed surgical biopsy. Pathologically, diffuse large B-cell lymphoma was diagnosed, but LAM was not detected. After she received six cycles of R-CHOP chemotherapy, FDG-PET turned negative and complete metabolic response was achieved. As LAM is reported to be silent for FDG-PET, unusual uptake of FDG is useful for identifying other neoplasms. For this case, FDG-PET was useful for the differential diagnosis and therapeutic evaluation.
DOI	10.1016/j.rmcr.2020.100999
PMID	32257785