ニイナミ　ヒロシ   Niinami Hiroshi   新浪　博    所属   医学部 医学科（東京女子医科大学病院）    職種   教授・基幹分野長
論文種別	症例報告
言語種別	英語
査読の有無	査読あり
表題	Unique haemodynamics in a patient with apicoaortic conduit dysfunction who underwent transcatheter aortic valve replacement.
掲載誌名	正式名：European heart journal cardiovascular Imaging 略　 称：Eur Heart J Cardiovasc Imaging ISSNコード：20472404/20472412
掲載区分	国外
出版社	Oxford University Press
巻・号・頁	21(6),pp.652
著者・共著者	DOMOTO Satoru†*, NAGAO Michinobu, ISOMURA Shogo, YAMAGUCHI Junichi, NIINAMI Hiroshi
担当区分	最終著者
発行年月	2020/06/01
概要	A 78-year-old woman was admitted with chronic heart failure. She underwent aortic valve bypass using a 23 mm-valved apicoaortic conduit (AAC) for severe aortic stenosis with porcelain aorta 7 years previously (Panel A). Echocardiography revealed a peak velocity of 4.2 m/s, a mean gradient of 41 mmHg, and no regurgitation within the AAC. Four-dimensional flow magnetic resonance imaging (MRI) revealed that the systematic circulation was mostly ejected from the AAC (Panel B and Supplementary data online, Video S1). AAC dysfunction was diagnosed, and we decided to perform transcatheter aortic valve replacement (TAVR) for the native aortic valve (NAV). A 26-mm Medtronic CoreValve Evolut R was implanted from the femoral route using the standard technique (Panel C). Four-dimensional flow MRI revealed that the systematic circulation was ejected from both the NAV and the AAC (Panel D and Supplementary data online, Video S2). We evaluated the haemodynamics using phase contrast MRI. The stroke volumes (SVs) from the AAC and NAV were 58 mL and 9 mL, respectively. The arch blood flow was retrograde from the descending aorta before TAVR (Panel E, the arrows indicate the flow direction and the numbers indicate the flow volume in millilitres). The SV from the NAV and AAC increased to 41 mL and 45 mL, respectively. The total SV increased, and the arch blood flow became antegrade after TAVR (Panel F). The haemodynamics after TAVR for AAC dysfunction remain unknown. This case highlights the unique haemodynamics in a patient who underwent TAVR with AAC dysfunction.
DOI	10.1093/ehjci/jez323
PMID	31985782