マサムネ　ケン   Masamune Ken   正宗　賢    所属   医学研究科 医学研究科 (医学部医学科をご参照ください)    職種   教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Clinical efficacy of bowel perfusion assessment during laparoscopic colorectal resection using laser speckle contrast imaging: A matched case–control study
掲載誌名	正式名：Asian journal of endoscopic surgery. 略　 称：Asian J Endosc Surg ISSNコード：17585902/17585910
掲載区分	国内
巻・号・頁	13(3),pp.329-335
著者・共著者	KOJIMA Shigehiro†*, SAKAMOTO Tsuguo, MATSUI Yutaka, NAMBU Kyojiro, MASAMUNE Ken
発行年月	2020/07
概要	Abstract Introduction Disadvantages of bowel perfusion assessment with indocyanine green fluorescence angiography include the need for a fluorophore and the subjective nature of the assessment. This study was performed to evaluate the clinical efficacy of bowel perfusion assessment using laser speckle contrast imaging (LSCI) during laparoscopic colorectal surgery. Methods The study population comprised the first 27 consecutive patients who underwent laparoscopic left‐sided colorectal resection with intraoperative perfusion assessment using LSCI. The operative outcomes of these patients were compared with those of a matched group of patients without perfusion assessment. We analyzed the flux data expressed in laser speckle perfusion units. Results After propensity score matching, we found no significant between‐group differences in the patients' characteristics with the exception of the cancer stage. No patients undergoing LSCI perfusion assessment developed anastomotic leakage, but five (18.5%) patients in the control group did, at a significantly higher rate in male patients (P = .042). There were no significant differences in other operative outcomes. The laser speckle perfusion unit values after ligating marginal vessels were significantly lower than before ligation (P < .01). Conclusions With respect to anastomotic leakage, LSCI may improve patient outcomes after colorectal surgery. This technique appears to be a superior tool with the advantages of measurement repeatability and quantitativity and no need for a fluorophore.
DOI	10.1111/ases.12759