ニイナミ　ヒロシ   Niinami Hiroshi   新浪　博    所属   医学部 医学科（東京女子医科大学病院）    職種   教授・基幹分野長
論文種別	症例報告
言語種別	英語
査読の有無	査読あり
表題	A case of severe peripartum cardiomyopathy requiring left ventricular assist device implantation despite the absence of late gadolinium enhancement on cardiovascular magnetic resonance imaging.
掲載誌名	正式名：Journal of cardiology cases 略　 称：J Cardiol Cases ISSNコード：18785409/18785409
掲載区分	国内
出版社	published by Elsevier B. V. on behalf of the Japanese College of Cardiology
巻・号・頁	21(1),pp.1-4
著者・共著者	TAKUWA-SHIOMI Chihiro†, OGISO Masataka*, ISOGAI Toshiaki, KATO Ken, TANAKA Hiroyuki, KIRIU Takahiro, MASUKAWA Ai, NIINAMI Hiroshi, HAGIWARA Nobuhisa
発行年月	2019/09/27
概要	Peripartum cardiomyopathy (PPCM) is a rare disorder in which left ventricular (LV) systolic dysfunction and symptoms of heart failure (HF) occur in the peripartum period. The time to potential recovery from severe remodeling of ventricular function is difficult to predict. Although lack of late gadolinium enhancement (LGE) in cardiovascular magnetic resonance (CMR) is reportedly associated with functional recovery of the LV in some cardiomyopathies, the impact of LGE in PPCM remains unclear. We herein report a case of a patient with PPCM who demonstrated rapidly worsened ventricular function, leading to requirement of a paracorporeal left ventricular assist device (LVAD) implantation despite absence of LGE in CMR. A 34-year-old Japanese patient, G2P2A0, expecting her third delivery following a full-term pregnancy, experienced heart failure. Severe LV dysfunction and PPCM were diagnosed. CMR showed no LGE. Although standard HF therapy and bromocriptine were given, her cardiac function failed to recover, and she eventually underwent paracorporeal LVAD implantation as a bridge to heart transplantation due to the impossibility of stopping the administration of inotropic agents. <Learning objective: The prognosis of peripartum cardiomyopathy without late gadolinium enhancement in cardiovascular magnetic resonance is reportedly better than that of cases with late gadolinium enhancement. Our patient, who did not have late gadolinium enhancement, showed rapidly worsening ventricular function, leading to the requirement of paracorporeal left ventricular assist device implantation. Patents with peripartum cardiomyopathy should be monitored vigilantly even if they have no late gadolinium enhancement.>.
DOI	10.1016/j.jccase.2019.09.011
PMID	31933696