ヤマナカ　ヒサシ   Yamanaka Hisashi   山中　寿    所属   医学部 医学科（東京女子医科大学病院）    職種   客員教授
論文種別	総説
言語種別	英語
査読の有無	査読あり
表題	A large observational cohort study of rheumatoid arthritis, IORRA: Providing context for today's treatment options.
掲載誌名	正式名：Modern rheumatology 略　 称：Mod Rheumatol ISSNコード：14397609/14397595
掲載区分	国外
巻・号・頁	pp.1-6
著者・共著者	Yamanaka Hisashi, Tanaka Eiichi, Nakajima Ayako, Furuya Takefumi, Ikari Katsunori, Taniguchi Atsuo, Inoue Eisuke, Harigai Masayoshi
担当区分	筆頭著者
発行年月	2019/10
概要	Real-world evidence, based on real-world data from routine clinical treatment, is becoming increasingly important for providing high-quality medical care. Large-scale cohort studies can provide useful access to some of this real-world evidence, as shown by the IORRA (Institute of Rheumatology, Rheumatoid Arthritis) cohort in Japan. This large cohort study of patients with rheumatoid arthritis (RA) has been surveying enrolled participants since its inception in 2000. In the last 19 years, it has served as a database for a wide range of research in areas including transitions in medical care at the clinical level, changes in therapeutic drugs, approaches to comorbidities, developments in pharmacoeconomics, and the effects of genomic information on treatment options. This research has resulted in the publication of 133 articles in English to date. IORRA monitors changes in the management of RA, and has quantified over time the daily experience of clinicians who provide routine medical care. Such observational databases, which reflect the reality of daily clinical practice, will become increasingly important and may provide a model for similar research in other disease areas.
DOI	10.1080/14397595.2019.1660028
PMID	31475852