カトウ　タカアキ   Katou Takaaki   加藤　孝章    所属   医学部 医学科（東京女子医科大学病院）    職種   非常勤講師
論文種別	症例報告
言語種別	英語
査読の有無	査読あり
表題	Inflammatory hepatocellular adenoma in a patient with Turner's syndrome: A case report.
掲載誌名	正式名：International journal of surgery case reports 略　 称：Int J Surg Case Rep ISSNコード：22102612/22102612
巻・号・頁	56,pp.5-9
著者・共著者	Nemoto Satoshi, Ariizumi Shun-Ichi, Kotera Yoshihito, Omori Akiko, Yamashita Shingo, Kato Taka-Aki, Aoyama Shota, Egawa Hiroto, Yamamoto Masakazu
発行年月	2019
概要	INTRODUCTION:Hepatocellular adenoma (HCA) is a rare benign tumor and is related to the use of an oral contraceptive pill. Turner's syndrome requires various hormone replacement therapies, including the pill which is used as a female hormone replacement therapy. Herein we report a case of Turner's syndrome with HCA treated by liver segmentectomy.PRESENTATION OF CASE:A 36-year-old woman with Turner's syndrome was treated with oral contraceptive pills as a female hormone replacement therapy for 20 years. She presented with fatigue and liver tumor. Liver tumors in the posterior lobe measuring 60 mm and 10 mm in diameter were detected on CT; hence, she was referred to our department. Both the tumors showed high intensity in the arterial phase, iso-intensity in the portal and late phases, and low intensity in the hepatobiliary phase on Gb-EOB-MRI. She was diagnosed with multiple HCAs and underwent segmentectomy Section 7. Pathologically, both the tumors were diagnosed as HCAs, and inflammatory markers were detected by immunohistochemistry. Thirteen months postoperatively, she was doing well and there was no evidence of recurrence of HCA without the pill.DISCUSSION:There is only one report of HCA in patients with TS (Espat et al., 2000). We reported a case of multiple HCAs in a patient with TS underwent hepatectomy.CONCLUSION:With the use of the contraceptive pill as a long-term female hormone replacement therapy for Turner's syndrome, careful attention is required for HCA.
DOI	10.1016/j.ijscr.2019.02.017
PMID	30798096