オカザキ　ケン   Okazaki Ken   岡崎　賢    所属   医学部 医学科（東京女子医科大学病院）    職種   教授・基幹分野長
論文種別	症例報告
言語種別	英語
査読の有無	査読あり
表題	Methotrexate-Related Lymphoproliferative Disorder Presenting with Severe Swelling of the Elbow Joint: A Case Report.
掲載誌名	正式名：JBJS case connector 略　 称：JBJS Case Connect ISSNコード：21603251/21603251
掲載区分	国外
巻・号・頁	7(3),pp.e65
著者・共著者	Hatano Takashi, Ohishi Masanobu, Yoshimoto Goichi, Yamauchi Moriyasu, Maekawa Akira, Yamamoto Hidetaka, Oda Yoshinao, Endo Makoto, Bekki Hirofumi, Matsunobu Tomoya, Nakashima Yasuharu, Okazaki Ken, Fukushi Jun-Ichi, Oyamada Akiko, Iwamoto Yukihide
発行年月	2017/07
概要	CASE:A patient with rheumatoid arthritis (RA) who was being treated with methotrexate (MTX) therapy presented with severe swelling of the left elbow. Magnetic resonance imaging showed a tumor-like lesion around the elbow joint. Fluorodeoxyglucose positron emission tomography indicated multiple lesions in the lung and the lymph nodes. An open biopsy of a cervical lymph node was performed, and MTX-related lymphoproliferative disorder (MTX-LPD) was diagnosed. After cessation of the MTX therapy, the elbow swelling regressed, and the patient was in remission of MTX-LPD.CONCLUSION:MTX-LPD should be considered in the differential diagnosis when a patient with RA develops severe joint swelling while on MTX therapy.
DOI	10.2106/JBJS.CC.17.00002
PMID	29252894