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イシズ アヤコ
ISHIZU Ayako
石津 綾子 所属 医学部 医学科 職種 教授・基幹分野長 |
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| Article types | Review article |
| Language | English |
| Peer review | Peer reviewed |
| Title | Aging of the hematopoietic stem cells niche. |
| Journal | Formal name：International journal of hematology Abbreviation：Int J Hematol ISSN code：18653774/09255710 |
| Domestic / Foregin | Foregin |
| Volume, Issue, Page | 100(4),pp.317-25 |
| Author and coauthor | Nakamura-Ishizu Ayako, Suda Toshio |
| Publication date | 2014/10 |
| Summary | Homeostasis of the hematopoietic system has its roots in the maintenance of hematopoietic stem cells (HSCs) in the bone marrow (BM). HSCs change both phenotypically and functionally with physiological age. The alterations noted in aged HSCs are thought to be a consequence of both cell-intrinsic and extrinsic changes. We review here the age-related changes that the BM microenvironment exerts on HSCs. |
| DOI | 10.1007/s12185-014-1641-8 |
| PMID | 25096220 |