イシズ　アヤコ   Ishizu Ayako   石津　綾子    所属   医学部 医学科    職種   教授・基幹分野長
論文種別	総説
言語種別	英語
査読の有無	査読あり
表題	Aging of the hematopoietic stem cells niche.
掲載誌名	正式名：International journal of hematology 略　 称：Int J Hematol ISSNコード：18653774/09255710
掲載区分	国外
巻・号・頁	100(4),pp.317-25
著者・共著者	Nakamura-Ishizu Ayako, Suda Toshio
発行年月	2014/10
概要	Homeostasis of the hematopoietic system has its roots in the maintenance of hematopoietic stem cells (HSCs) in the bone marrow (BM). HSCs change both phenotypically and functionally with physiological age. The alterations noted in aged HSCs are thought to be a consequence of both cell-intrinsic and extrinsic changes. We review here the age-related changes that the BM microenvironment exerts on HSCs.
DOI	10.1007/s12185-014-1641-8
PMID	25096220