イイダ　トモヒロ   Iida Tomohiro   飯田　知弘    所属   医学部 医学科（東京女子医科大学病院）    職種   教授・基幹分野長
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Giant retinal pigment epithelial tear associated with fluid overload due to end-stage diabetic kidney disease.
掲載誌名	正式名：American journal of ophthalmology case reports 略　 称：Am J Ophthalmol Case Rep ISSNコード：24519936/24519936
掲載区分	国外
巻・号・頁	5,pp.44-47
著者・共著者	Kameda Yusuke, Hirose Akira, Iida Tomohiro, Uchigata Yasuko, Kitano Shigehiko
発行年月	2017/04
概要	Purpose:To report a case of a giant retinal pigment epithelial (RPE) tear associated with fluid overload in a patient with diabetic macular edema (DME) and kidney disease.Observations:A 60-year-old man with type 2 diabetes mellitus and end-stage diabetic kidney disease who had gained weight because of fluid overload complained of a visual disturbance in the left eye that had started a few days earlier. The left fundus showed a RPE defect in two temporal quadrants under an extensive serous retinal detachment (SRD) with exacerbation of the original DME. Seven days later, he was admitted for severe edema and pleural effusion. No overt signs of congestive heart failure were noted. On admission, the RPE defect had markedly widened to involve the macula. Spectral-domain optical coherence tomography images showed substantial intraretinal fluid and an extensive SRD with rolled edges of the retinal pigment epithelium, which led to the diagnosis of a RPE tear. The fluid under the SRD was absorbed on the fourth hospital day and the substantial intraretinal fluid resolved on the eleventh day after systemic management of fluid overload only without ophthalmic treatment. The change in the appearance of the RPE area was minimal and the visual field defect remained even after 6 months.Conclusions and importance:A RPE tear may develop in association with fluid overload in patients with diabetes.
DOI	10.1016/j.ajoc.2016.11.004
PMID	29503946