マルコ　イチロウ   Maruko Ichirou   丸子　一朗    所属   医学部 医学科（東京女子医科大学病院）    職種   准教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Subthreshold 577 nm micropulse laser treatment for central serous chorioretinopathy.
掲載誌名	正式名：PloS one 略　 称：PLoS One ISSNコード：19326203/19326203
掲載区分	国外
巻・号・頁	12(8),pp.e0184112
著者・共著者	Maruko Ichiro, Koizumi Hideki, Hasegawa Taiji, Arakawa Hisaya, Iida Tomohiro
担当区分	筆頭著者
発行年月	2017/08
概要	PURPOSE:To compare the efficacy of the subthreshold micropulse laser (SML) to conventional laser (CL) in treating focal leakages of the retinal pigment epithelium (RPE) in the eyes with central serous chorioretinopathy (CSC).METHODS:Twenty-nine eyes of 28 patients with CSC and typical focal leakage were treated with CL or SML. Both treatments were made with a 577 nm yellow laser (CL: NIDEK MC-500, SML: IRIDEX IQ577). The percentage of eyes with a complete resolution, the distance of the laser burns from the fovea, and injury of the RPE after treatment were studied.RESULTS:A complete resolution was seen in 10 of 15 eyes (66.7%) after CL and 9 of 14 eyes (64.3%) after SML (P = 0.89). The average distance from the foveal center to the leakage point was 1282±596 μm for eyes treated with CL and 1271±993 μm for eyes treated with SML (P = 0.4). Only three eyes treated with SML had treatment sites within 500 μm of the fovea. RPE damage determined by fundus autofluorescence was found in all eyes treated with CL and only one eye treated with SML (P<.01).CONCLUSIONS:SML achieved equivalent therapeutic effects as CL but without RPE damage in eyes with CSC.
DOI	10.1371/journal.pone.0184112
PMID	28850595