シヨウダ モリオ   Shiyouda Morio
  庄田 守男
   所属   医学部 医学科(東京女子医科大学病院)
   職種   寄附部門教授
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 Prognosis after lead extraction in patients with cardiac implantable electronic devices infection: Comparison of lead-related infective endocarditis with pocket infection in a Japanese single-center experience.
掲載誌名 正式名:Journal of arrhythmia
略  称:J Arrhythm
ISSNコード:18804276/18832148
掲載区分国内
出版社 Japanese Heart Rhythm Society
巻・号・頁 35(4),pp.654-663
著者・共著者 Nishii Nobuhiro, Morimoto Yoshimasa, Miyoshi Akihito, Tsukuda Saori, Miyamoto Masakazu, Kawada Satoshi, Nakagawa Koji, Watanabe Atsuyuki, Nakamura Kazufumi, Morita Hiroshi, Morimatsu Hiroshi, Kusano Nobuchika, Kasahara Shingo, Shoda Morio, Ito Hiroshi
発行年月 2019/08
概要 Background:The increase in the use of cardiac implantable electronic devices (CIEDs) has been associated with an increase in CIED-related infections. Transvenous lead extraction is safe and effective for patients with CIED-related infections; however, the mortality rate in these patients is high. The prognosis after transvenous lead extraction in Japanese patients, especially those with lead-related infective endocarditis, has not been evaluated. Then, the purpose of this study is to clarify the prognosis after transvenous lead extraction in Japanese patients with CIED-related infections at a single Japanese center.

Methods:A total of 107 patients who underwent transvenous lead extraction were retrospectively reviewed. The patients were divided into a lead-related infective endocarditis group (n = 32) and a pocket infection group (n = 75). Procedure success rate and prognosis after lead extraction were evaluated between the two groups.

Results:Procedure success rate was not significantly different between the groups. There were no deaths associated with the procedure or with infection. The survival rate was not significantly different at 1 year or at a median of 816 days (lead-related infective endocarditis vs pocket infection; 93.7% vs 94.7%, P = 1.000; 78.1% vs 81.3%, P = 0.791) Time to reimplantation and duration of hospital stay and antibiotics therapy were significantly longer for patients with lead-related infective endocarditis.

Conclusion:In this study, the prognosis for patients with lead-related infective endocarditis after transvenous lead extraction was favorable. Thus, extraction should be strongly recommended, even if the general condition of the patient is poor.
DOI 10.1002/joa3.12164
PMID 31410236