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マルヤマ タカシ
MARUYAMA Takashi
丸山 隆志 所属 医学部 医学科（東京女子医科大学病院） 職種 非常勤講師 |
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| 論文種別 | 原著 |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | Impact of connectivity between the pars triangularis and orbitalis on identifying the frontal language area in patients with dominant frontal gliomas. |
| 掲載誌名 | 正式名：Neurosurgical review 略 称：Neurosurg Rev ISSNコード：(1437-2320)0344-5607(Linking) |
| 掲載区分 | 国外 |
| 出版社 | Springer |
| 巻・号・頁 | 43(2),pp.537-545 |
| 著者・共著者 | SAITO Taiichi†*, MURAGAKI Yoshihiro, TAMURA Manabu, MARUYAMA Takashi, NITTA Masayuki, TSUZUKI Shunsuke, KAWAMATA Takakazu |
| 発行年月 | 2020/04 |
| 概要 | We have previously revealed that identification of the frontal language area (FLA) can be difficult in patients with dominant frontal glioma involving the pars triangularis (PT). The present study added new cases and performed additional analyses. We noticed a new finding that the presence of extension to the pars orbitalis (POr) was associated with negative response to the FLA. The aim of the present study was to evaluate the impact of PT involvement with extension to the POr on the failure to identify the FLA. From 2000 to 2017, awake craniotomy was performed on 470 patients. Of these patients, the present study included 148 consecutive patients with frontal glioma on the dominant side. We evaluated whether tumors involved the PT or extended to the POr. Thirty one of 148 patients showed involvement of the PT, and we examined the detailed characteristics of these 31 patients. The rate of negative response for the FLA was 61% in patients with involvement of the PT. In 31 patients with frontal glioma involving the PT, univariate analyses showed significant correlation between extension to the POr and failure to identify the FLA (P = 0.0070). Similarly, multivariate analysis showed only extension to the POr correlated significantly with failure to identify the FLA (P = 0.0129). We found new evidence that extension to the POr which impacts connectivity between the PT and POr correlated significantly with negative response to the FLA of patients with dominant frontal glioma. |
| DOI | 10.1007/s10143-018-1052-z |
| PMID | 30415305 |