ナンケ　ユキ   NANKE Yuki   南家　由紀    所属   看護学部 看護学科    職種   教授
論文種別	症例報告
言語種別	英語
査読の有無	査読あり
表題	Pancytopenia and colitis with Clostridium difficile in a rheumatoid arthritis patient taking methotrexate, antibiotics and non-steroidal anti-inflammatory drugs.
掲載誌名	正式名：Clinical rheumatology 略　 称：Clin Rheumatol ISSNコード：(0770-3198)0770-3198(Linking)
掲載区分	国外
巻・号・頁	20(1),pp.73-5
著者・共著者	Nanke Y, Kotake S, Akama H, Tomii M, Kamatani N
発行年月	2001
概要	Methotrexate (MTX) is widely used despite its side-effects. We describe a rheumatoid arthritis (RA) patient taking low-dose MTX who developed severe pancytopenia and colitis with Clostridium difficile after the administration of antibiotics for acute pyelonephritis. Our case suggests that low-dose MTX may seriously interact with antibiotics and that these side-effects should always be considered when RA patients are treated with MTX and antibiotics.
DOI	10.1007/PL00011187
PMID	11254248