ヤマウチ カヅヨ
YAMAUCHI Kadzuyo
山内 かづ代 所属 医学部 医学科 職種 評議員 |
|
論文種別 | 原著 |
言語種別 | 英語 |
査読の有無 | 査読あり |
表題 | Tumor necrosis factor-alpha in the nucleus pulposus mediates radicular pain, but not increase of inflammatory peptide, associated with nerve damage in mice. |
掲載誌名 | 正式名:Spine 略 称:Spine (Phila Pa 1976) ISSNコード:(1528-1159)0362-2436(Linking) |
掲載区分 | 国外 |
巻・号・頁 | 33(17),pp.1836-42 |
著者・共著者 | Yamashita Masaomi, Ohtori Seiji, Koshi Takana, Inoue Gen, Yamauchi Kazuyo, Suzuki Munetaka, Takahashi Kazuhisa |
発行年月 | 2008/08 |
概要 | In this study TNF-alpha contained in the NP was important for the production of radicular pain accompanied by long-lasting degeneration of DRG neurons. However, other cytokines in the NP and nerve compression may also play important roles in pain transmission. In this model system, TNF-alpha in the NP appears to mediate pain, but not cause an increase in CGRP in the DRG neurons. |
DOI | 10.1097/BRS.0b013e31817bab2a |
PMID | 18670336 |