ヤマウチ カヅヨ   YAMAUCHI Kadzuyo
  山内 かづ代
   所属   医学部 医学科
   職種   評議員
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 Tumor necrosis factor-alpha in the nucleus pulposus mediates radicular pain, but not increase of inflammatory peptide, associated with nerve damage in mice.
掲載誌名 正式名:Spine
略  称:Spine (Phila Pa 1976)
ISSNコード:(1528-1159)0362-2436(Linking)
掲載区分国外
巻・号・頁 33(17),pp.1836-42
著者・共著者 Yamashita Masaomi, Ohtori Seiji, Koshi Takana, Inoue Gen, Yamauchi Kazuyo, Suzuki Munetaka, Takahashi Kazuhisa
発行年月 2008/08
概要 In this study TNF-alpha contained in the NP was important for the production of radicular pain accompanied by long-lasting degeneration of DRG neurons. However, other cytokines in the NP and nerve compression may also play important roles in pain transmission. In this model system, TNF-alpha in the NP appears to mediate pain, but not cause an increase in CGRP in the DRG neurons.
DOI 10.1097/BRS.0b013e31817bab2a
PMID 18670336