ヤマウチ　カヅヨ   YAMAUCHI Kadzuyo   山内　かづ代    所属   医学部 医学科    職種   評議員
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Clinical applications of diffusion magnetic resonance imaging of the lumbar foraminal nerve root entrapment.
掲載誌名	正式名：European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 略　 称：Eur Spine J ISSNコード：(1432-0932)0940-6719(Linking)
掲載区分	国外
巻・号・頁	19(11),pp.1874-82
著者・共著者	Eguchi Yawara, Ohtori Seiji, Yamashita Masaomi, Yamauchi Kazuyo, Suzuki Munetaka, Orita Sumihisa, Kamoda Hiroto, Arai Gen, Ishikawa Tetsuhiro, Miyagi Masayuki, Ochiai Nobuyasu, Kishida Shunji, Masuda Yoshitada, Ochi Shigehiro, Kikawa Takashi, Takaso Masashi, Aoki Yasuchika, Toyone Tomoaki, Suzuki Takane, Takahashi Kazuhisa
発行年月	2010/11
概要	Diffusion-weighted imaging (DWI) can provide valuable structural information about tissues that may be useful for clinical applications in evaluating lumbar foraminal nerve root entrapment. Our purpose was to visualize the lumbar nerve root and to analyze its morphology, and to measure its apparent diffusion coefficient (ADC) in healthy volunteers and patients with lumbar foraminal stenosis using 1.5-T magnetic resonance imaging. Fourteen patients with lumbar foraminal stenosis and 14 healthy volunteers were studied. Regions of interest were placed at the fourth and fifth lumbar root at dorsal root ganglia and distal spinal nerves (at L4 and L5) and the first sacral root and distal spinal nerve (S1) on DWI to quantify mean ADC values. The anatomic parameters of the spinal nerve roots can also be determined by neurography. In patients, mean ADC values were significantly higher in entrapped roots and distal spinal nerve than in intact ones. Neurography also showed abnormalities such as nerve indentation, swelling and running transversely in their course through the foramen. In all patients, leg pain was ameliorated after selective decompression (n = 9) or nerve block (n = 5). We demonstrated the first use of DWI and neurography of human lumbar nerves to visualize and quantitatively evaluate lumbar nerve entrapment with foraminal stenosis. We believe that DWI is a potential tool for diagnosis of lumbar nerve entrapment.
DOI	10.1007/s00586-010-1520-9
PMID	20632042