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ヤマウチ カヅヨ
YAMAUCHI Kadzuyo
山内 かづ代 所属 医学部 医学科 職種 評議員 |
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| 論文種別 | 原著 |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | Effect of applying p75NTR saporin to a punctured intervertebral disc on calcitonin gene-related peptide expression in rat dorsal root ganglion neurons. |
| 掲載誌名 | 正式名：Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 略 称：J Orthop Sci ISSNコード：(1436-2023)0949-2658(Linking) |
| 掲載区分 | 国外 |
| 巻・号・頁 | 15(3),pp.407-13 |
| 著者・共著者 | Sugiura Ai, Ohtori Seiji, Yamashita Masaomi, Yamauchi Kazuyo, Inoue Gen, Suzuki Munetaka, Norimoto Masaki, Orita Sumihisa, Eguchi Yawara, Kuniyoshi Kazuki, Ochiai Nobuyasu, Kishida Shunji, Takaso Masashi, Aoki Yasuchika, Ishikawa Tetsuhiro, Arai Gen, Miyagi Masayuki, Kamoda Hiroto, Nakamura Junichi, Takahashi Kazuhisa |
| 担当区分 | 責任著者 |
| 発行年月 | 2010/05 |
| 概要 | Half of the DRG neurons innervating the discs were positive for CGRP in the puncture + saline group. CGRP is important for mediating inflammatory and nerve-injured pain and may be important in discogenic pain. However, p75NTR saporin suppressed CGRP expression in DRG neurons. Therefore, p75NTR may be an important receptor for mediating discogenic pain via CGRP expression. |
| DOI | 10.1007/s00776-010-1469-x |
| PMID | 20559810 |