ヤマウチ カヅヨ   YAMAUCHI Kadzuyo
  山内 かづ代
   所属   医学部 医学科
   職種   評議員
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 Anti-RANKL antibodies decrease CGRP expression in dorsal root ganglion neurons innervating injured lumbar intervertebral discs in rats.
掲載誌名 正式名:European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
略  称:Eur Spine J
ISSNコード:(1432-0932)0940-6719(Linking)
掲載区分国外
巻・号・頁 24(9),pp.2017-22
著者・共著者 Sato Masashi, Inage Kazuhide, Sakuma Yoshihiro, Sato Jun, Orita Sumihisa, Yamauchi Kazuyo, Eguchi Yawara, Ochiai Nobuyasu, Kuniyoshi Kazuki, Aoki Yasuchika, Nakamura Junichi, Miyagi Masayuki, Suzuki Miyako, Kubota Gou, Sainoh Takeshi, Fujimoto Kazuki, Shiga Yasuhiro, Abe Koki, Kanamoto Hiroto, Inoue Gen, Takahashi Kazuhisa, Ohtori Seiji
発行年月 2015/09
概要 TNF-α and IL-6 in the injured discs increased and CGRP expression increased in DRG neurons innervating injured discs, and antibodies to RANKL could suppress this increased TNF-α, IL-6, and CGRP expression. RANKL may be a therapeutic target for pain control in patients with lumbar disc degeneration.
DOI 10.1007/s00586-015-4058-z
PMID 26071945