ヤマウチ　カヅヨ   YAMAUCHI Kadzuyo   山内　かづ代    所属   医学部 医学科    職種   評議員
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Diffusion tensor imaging of lumbar spinal nerve in subjects with degenerative lumbar disorders.
掲載誌名	正式名：Magnetic resonance imaging 略　 称：Magn Reson Imaging ISSNコード：(1873-5894)0730-725X(Linking)
掲載区分	国外
巻・号・頁	33(8),pp.956-61
著者・共著者	Oikawa Yasuhiro, Eguchi Yawara, Inoue Gen, Yamauchi Kazuyo, Orita Sumihisa, Kamoda Hiroto, Ishikawa Tetsuhiro, Miyagi Masayuki, Suzuki Miyako, Sakuma Yoshihiro, Kubota Go, Inage Kazuhide, Saino Takeshi, Sato Hirotaka, Ando Hiroki, Kojima Masatoshi, Okumura Kenichiro, Masuda Yoshitada, Watanabe Atsuya, Takahashi Kazuhisa, Ohtori Seiji
発行年月	2015/10
概要	Recently several authors have reported that diffusion tensor imaging (DTI) might provide a new understanding of sciatica. The purpose of this study was to investigate the clinical feasibility of DTI for the evaluation of lumbar spinal nerve of patients with sciatica associated with lumbar degenerative disorders. Thirty-four patients (25men, mean age63. 3years) with degenerated lumbar disease, 14 patients with lumbar spinal stenosis with foraminal stenosis, 12 with lumbar spinal stenosis without foraminal stenosis, five with lumbar disc herniation, two with discogenic low back pain, and one with spondylolysis who underwent 3.0T magnetic resonance (MR) imaging and surgical treatment were included in the present study. Fractional anisotropy (FA) was calculated from an FA map, and tractography was investigated. In asymptomatic nerves, tractography showed all L3-S1 spinal nerve roots clearly. Abnormalities of tractography were classified into three types by shape; "Disrupted", "Narrowing", and "Tapering". More abnormalities of tractography were found in patients with lumbar spinal stenosis, and especially in patients with foraminal stenosis. The disrupted type was the most common. The mean FA of entrapped symptomatic nerves was less than seen on the intact side. This study demonstrates that tractography shows abnormal findings for nerve roots in lumbar spinal degeneration and that FA decreases in symptomatic roots. DTI may offer not only morphological evaluation, but also quantitative evaluation. We believe that DTI can be used as a tool for the diagnosis of lumbar spinal degenerative disease.
DOI	10.1016/j.mri.2015.05.002
PMID	25979227