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キバヤシ カズヒコ
Kibayashi Kazuhiko
木林 和彦 所属 医学部 医学科 職種 教授・基幹分野長 |
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| 論文種別 | 原著 |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | Quantification of Methamphetamine in Mouse Thighbones Buried in Soil. |
| 掲載誌名 | 正式名：Journal of forensic sciences 略 称：J Forensic Sci ISSNコード：(1556-4029)0022-1198(Linking) |
| 掲載区分 | 国外 |
| 巻・号・頁 | 62(6),pp.1154-1158 |
| 著者・共著者 | Nakao Ken-ichiro†*, Tatara Yuki, Kibayashi Kazuhiko |
| 担当区分 | 最終著者 |
| 発行年月 | 2017/04 |
| 概要 | Bone samples are used for analysis of drugs in decomposed or skeletonized bodies. Toxicological analyses of buried bones are important for determining the causes and circumstances of death. In this study, methamphetamine and amphetamine concentrations in heart blood, thigh muscles, and thighbones were analyzed using solid-phase extraction with liquid chromatography-tandem mass spectrometry. Methamphetamine concentrations in heart blood, thigh muscle, and thighbone ranged from 0.041 to 0.873 μg/mL, 0.649 to 2.623 μg/g, and 56.543 to 643.371 μg/g, respectively. Thighbone concentrations were significantly higher than those in heart blood or thigh muscles were. Methamphetamine concentrations in buried thighbone (4.010-45.785 μg/g) were significantly lower than those of unburied thighbones were (56.543-643.371 μg/g). Methamphetamine and amphetamine were detected in thighbones buried for 7-180 days. These findings indicate that the methamphetamine concentrations in bone are higher and decrease after burial in soil. |
| DOI | 10.1111/1556-4029.13458 |
| PMID | 28436031 |