ウラセ　コウコ   Urase Kouko   浦瀬　香子    所属   医学部 医学科    職種   助教
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Spatial expression of Sonic hedgehog in the lung epithelium during branching morphogenesis.
掲載誌名	正式名：Biochemical and biophysical research communications 略　 称：Biochem Biophys Res Commun ISSNコード：(0006-291X)0006-291X(Linking)
掲載区分	国外
巻・号・頁	225(1),pp.161-6
著者・共著者	Urase K, Mukasa T, Igarashi H, Ishii Y, Yasugi S, Momoi M Y, Momoi T
担当区分	筆頭著者
発行年月	1996/08
概要	Sonic hedgehog (Shh), a homologue of Drosophila hedgehog, was specifically expressed in lung epithelium during branching morphogenesis, but was not uniformly expressed in lung epithelium. Shh was intensely expressed in the distal tips of the bronchial tubes during branching morphogenesis, and Shh was localized on the apical side of the epithelium. On the other hand, Bmp-4, one of the target genes of Shh, was also specifically expressed in the epithelium at the branching point. These results suggest that Shh and Bmp-4 are involved in the branching morphogenesis of lung epithelium.
DOI	10.1006/bbrc.1996.1147
PMID	8769111