イシイ　ヤスオ   Ishii Yasuo   石井　泰雄    所属   医学部 医学科    職種   講師
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Sox3 expression defines a common primordium for the epibranchial placodes in chick.
掲載誌名	正式名：Developmental biology 略　 称：Dev Biol ISSNコード：(0012-1606)0012-1606(Linking)
掲載区分	国外
巻・号・頁	236(2),pp.344-53
著者・共著者	Ishii Y, Abu-Elmagd M, Scotting P J
担当区分	筆頭著者
発行年月	2001/08
概要	The epibranchial placodes are ectodermal thickenings that generate sensory neurons of the distal ganglia of the branchial nerves. Although significant advances in our understanding of neurogenesis from the placodes have recently been made, the events prior to the onset of neurogenesis remain unclear. We found that chick Sox3 (cSox3) shows a highly dynamic pattern of expression before becoming confined to the final placodes: one pre-otic (geniculate) and three post-otic (one petrosal and two nodose) placodes. A fate-mapping study using lipophilic dyes revealed that all post-otic placodes arise within a single broad cSox3-positive domain, where cSox3 expression and epithelial thickness will be retained only in much smaller final neurogenic placodes. The data presented here suggest that post-otic placodes are remnants of a common primordium defined as a discrete domain of cSox3 expression.
DOI	10.1006/dbio.2001.0318
PMID	11476576