シヨウダ　モリオ   Shiyouda Morio   庄田　守男    所属   医学部 医学科（東京女子医科大学病院）    職種   寄附部門教授
論文種別	原著
言語種別	英語
査読の有無	査読なし
表題	An overlap of Brugada syndrome and arrhythmogenic right ventricular cardiomyopathy/dysplasia.
掲載誌名	正式名：Journal of arrhythmia 略　 称：J Arrhythm ISSNコード：18804276
掲載区分	国外
出版社	Elsevier
巻・号・頁	32(1),pp.70-73
著者・共著者	KATAOKA Shohei†, SERIZAWA Naoki, KITAMURA Kazutaka, SUZUKI Atsushi, SUZUKI Tsuyoshi, SHIGA Tsuyoshi, SHODA Morio, HAGIWARA Nobuhisa
発行年月	2016/02
概要	Overlapping characteristics of Brugada syndrome (BrS) and arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) have been reported in recent studies, but little is known about the overlapping disease state of BrS and ARVC/D. A 36-year-old man, hospitalized at our institution for syncope, presented with this overlapping disease state. The electrocardiogram showed spontaneous coved-type ST-segment elevation, and ventricular fibrillation was induced by right ventricular outflow tract stimulation in an electrophysiological study. BrS was subsequently diagnosed; additionally, the presence of epsilon-like waves and right ventricular structural abnormalities met with the 2010 revised task force criteria for ARVC/D. After careful investigation for both BrS and ARVC/D, an implantable cardioverter defibrillator was inserted in the patient. This case revealed 2 important clinical findings: (1) BrS and ARVC/D clinical features can coexist in a single patient, and EPS might be useful for determining the phenotype of overlapping disease (e.g., BrS-like or ARVC/D-like). (2) An overlapping disease state of BrS and ARVC/D can change phenotypically during its clinical course. Therefore, careful examination and attentive follow-up are required for patients with BrS or ARVC/D.
DOI	10.1016/j.joa.2015.10.007
PMID	26949435