サイトウ　タイイチ   Saitou Taiichi   齋藤　太一    所属   医学研究科 医学研究科 (医学部医学科をご参照ください)    職種   非常勤講師
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Role of PROPELLER diffusion weighted imaging and apparent diffusion coefficient in the diagnosis of sellar and parasellar lesions.
掲載誌名	正式名：European journal of radiology 略　 称：Eur J Radiol ISSNコード：1872-7727(Electronic)0720-048X(Linking)
掲載区分	国外
巻・号・頁	74(3),pp.420-7
著者・共著者	Mahmoud Omar M, Tominaga Atsushi, Amatya Vishwa Jeet, Ohtaki Megu, Sugiyama Kazuhiko, Saito Taiichi, Sakoguchi Tetsuhiko, Kinoshita Yasuyuki, Shrestha Prabin, Abe Nobukazu, Akiyama Yuji, Takeshima Yukio, Arita Kazunori, Kurisu Kaoru, Yamasaki Fumiyuki
発行年月	2010/06
概要	OBJECTIVE:To evaluate the role of the apparent diffusion coefficient (OBJECTIVE:ADC) using periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) diffusion weighted imaging (DWI) in the differentiation between sellar and parasellar mass lesions.MATERIALS AND METHODS:The study protocol was approved by our institutional review board. We retrospectively studied 60 patients with sellar and parasellar lesions who had undergone PROPELLER DWI on a 3-T MR imager. Conventional MRI findings were expressed as the ratio of signal intensity (SI) in the lesions to the normal white matter and the degree of contrast enhancement. ADC values were calculated as the minimum (ADC-MIN), mean (ADC-MEAN), and maximum (ADC-MAX). All patients underwent surgery and all specimens were examined histologically. Logistic discriminant analysis was performed by using the SI ratios on T1- and T2-weighted images (T1-WI, T2-WI), the degree of enhancement, and absolute ADC values as independent variables.RESULTS:ADC-MIN of hemorrhagic pituitary adenomas was lower than of the other lesions with similar appearance on conventional MRI (non-hemorrhagic pituitary adenomas, craniopharyngiomas, Rathke's cleft cysts; accuracy 100%); the useful cut-off value was 0.700 x 10(-3)mm(2)/s. ADC-MAX of meningiomas was lower than of non-hemorrhagic pituitary adenomas (accuracy 90.3%; pRESULTS:<RESULTS:0.01). ADC-MIN of craniopharyngiomas was lower than of Rathke's cleft cysts (accuracy 100%; pRESULTS:<RESULTS:0.05).CONCLUSION:As PROPELLER DWI is less sensitive to susceptibility artifacts than single-shot echoplanar DWI, it is more useful in the examination of sellar and parasellar lesions. Calculation of the ADC values helps to differentiate between various sellar and parasellar lesions.
DOI	10.1016/j.ejrad.2009.03.031
文献番号	19394778